Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

For decades, biologists treated DNA as a static string of letters, a linear code that cells read like text on a page. A new wave of research is forcing a rethink, showing that the three-dimensional ...

Researchers at Duke University used CRISPR technologies to discover previously unannotated stretches of DNA in the ‘dark genome’ that are responsible for controlling how cells sense and respond to the ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

Cancer isn't just about broken genes—it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...