The production of red blood cells from stem cells has emerged as a transformative approach to address chronic blood shortages and meet the increasing demand for transfusion therapies. By harnessing ...

Researchers at University of California San Diego School of Medicine and their colleagues have developed the first ...

A breakthrough in the understanding of how mammals create red blood cells could lead to opportunities for artificial blood to be created at scale for the first time. The study was led by Dr. Julia ...

A research team has discovered a mechanism in which blood stem cells respond to acute, severe anemia, through lipoprotein metabolism modification. It has been known how immediate erythroid precursors ...

Erythropoietin, the protein that drives red blood cell formation, also induces tolerance in dendritic cells, leading to the ...

Scientists have been working on the artificial production of blood for several decades. Now, researchers from the University of Konstanz and Queen Mary University of London have taken an important ...

The amino acid glutamine plays an unexpected role in erythropoiesis, the differentiation of erythroid progenitor cells into mature red blood cells. Ordinarily, glutamine is broken down by stem cells ...

Researchers have developed a method to confidently produce blood cell precursors from stem cells in mice, by activating a set of seven key genes in the laboratory. The team takes a step forward ...

Red blood cells are the most abundant cells in the body. It has long been known that when red blood cells break down or anemia occurs due to bleeding, the hormone erythropoietin (EPO) increases, ...

Hemoglobin serves as the essential protein in red blood cells responsible for transporting oxygen from the lungs to tissues throughout the body. When levels fall below normal ranges (typically below ...

When acute anemia occurs, very low-density lipoproteins (VLDL), which are involved in lipid transport, are broken down, releasing apolipoprotein E (ApoE). ApoE binds to its receptor (VLDLR) present on ...