A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...

Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...

A research group led by Drs. Shusuke Tada and Takashi Tsuyama at the Department of Molecular Biology, Faculty of ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

When you're feeling under the weather, almost any kind of soup can be soothing. But research suggests that a classic mix of chicken, broth and other nourishing ingredients may be the best soup to cut ...

Accurate genome duplication is essential for all living cells. In Escherichia coli and most other bacteria, a circular chromosome is replicated bidirectionally at high speed. Two replisomes, assembled ...

A University of Iowa-led study uncovered a unique double-ring structure of the DNA repair protein RAD52 that plays a critical role in protecting stalled DNA replication in cancer cells with repair ...

Researchers from Spain and the US discovered how cells repair broken DNA replication sites, which is vital for preventing cancer-related genome issues They identified key proteins essential for fixing ...

Abstract: Currently, one of the most effective techniques to study the mechanisms of DNA replication is using the electron microscopy. Typical imaging experiments result in terabytes of image data, ...